Apertura 2021
Apertura 2021 Primera Division
| Fecha #1 | 02-05-2021 08:00 | Cerveceros | 3 : 4 | Union SC 01 | |
| 02-05-2021 08:00 | Deportivo Durango | 1 : 4 | Locos Villahermosa | ||
| 02-05-2021 09:40 | Latinos | 3 : 1 | Paris FC | ||
| 02-05-2021 09:40 | Deportivo Niupi | 3 : 0 | Michoacan | ||
| 02-05-2021 11:20 | Cruz Azul | 3 : 2 | Deportivo River | ||
| 02-05-2021 13:00 | Atlas | 0 : 1 | Monarcas San Rafael | ||
| Fecha #2 | 09-05-2021 08:00 | Deportivo Durango | 3 : 0 | Paris FC | |
| 09-05-2021 08:00 | C. D. Padua | 2 : 1 | Monarcas San Rafael | ||
| 09-05-2021 09:40 | Atlas | 1 : 1 | Cerveceros | ||
| 09-05-2021 09:40 | Hayden F. C. | 0 : 3 | Latinos | ||
| 09-05-2021 09:40 | Deportivo Niupi | 5 : 0 | Locos Villahermosa | ||
| 09-05-2021 11:20 | Deportivo River | 2 : 1 | Union SC 01 | ||
| 09-05-2021 11:20 | Cruz Azul | 3 : 1 | Morelos FC | ||
| Fecha #3 | 16-05-2021 00:00 | Hayden F. C. | 1 : 0 | Morelos FC | |
| 16-05-2021 08:00 | C. D. Padua | 4 : 1 | Paris FC | ||
| 16-05-2021 08:00 | Cerveceros | 2 : 1 | Deportivo Durango | ||
| 16-05-2021 09:40 | Atlas | 0 : 3 | Locos Villahermosa | ||
| 16-05-2021 09:40 | Cruz Azul | 2 : 2 | Deportivo Niupi | ||
| 16-05-2021 11:20 | Deportivo River | 0 : 1 | Latinos | ||
| 16-05-2021 11:20 | Monarcas San Rafael | 4 : 1 | Union SC 01 | ||
| Fecha #4 | 23-05-2021 00:00 | Michoacan | 0 : 1 | Morelos FC | |
| 23-05-2021 08:00 | Atlas | 1 : 7 | C. D. Padua | ||
| 23-05-2021 08:00 | Deportivo Durango | 0 : 3 | Paris FC | ||
| 23-05-2021 09:40 | Latinos | 4 : 0 | Locos Villahermosa | ||
| 23-05-2021 09:40 | Cerveceros | 0 : 2 | Deportivo Niupi | ||
| 23-05-2021 11:20 | Los Birriondos | 1 : 1 | Monarcas San Rafael | ||
| 23-05-2021 11:20 | Cruz Azul | 4 : 1 | Union SC 01 | ||
| 23-05-2021 11:20 | Deportivo River | 1 : 5 | Hayden F. C. | ||
| Fecha #5 | 30-05-2021 08:00 | C. D. Padua | 0 : 2 | Cerveceros | |
| 30-05-2021 08:00 | Monarcas San Rafael | 1 : 1 | Paris FC | ||
| 30-05-2021 09:40 | Atlas | 1 : 1 | Deportivo Durango | ||
| 30-05-2021 09:40 | Inter | 2 : 3 | Latinos | ||
| 30-05-2021 11:20 | Cruz Azul | 2 : 3 | Hayden F. C. | ||
| 30-05-2021 11:20 | Deportivo River | 2 : 3 | Los Birriondos | ||
| Fecha #6 | 06-06-2021 08:00 | C. D. Padua | 6 : 0 | Deportivo Durango | |
| 06-06-2021 08:00 | Hayden F. C. | 4 : 0 | Paris FC | ||
| 06-06-2021 09:40 | Deportivo Niupi | 2 : 2 | Latinos | ||
| 06-06-2021 09:40 | Cerveceros | 1 : 1 | Locos Villahermosa | ||
| 06-06-2021 09:40 | Deportivo River | 3 : 1 | Monarcas San Rafael | ||
| 06-06-2021 11:20 | Inter | 1 : 1 | Union SC 01 | ||
| 06-06-2021 11:20 | Atlas | 1 : 0 | Morelos FC | ||
| 06-06-2021 11:20 | Cruz Azul | 1 : 2 | Los Birriondos | ||
| Fecha #7 | 13-06-2021 08:00 | Cerveceros | 1 : 2 | Monarcas San Rafael | |
| 13-06-2021 08:00 | Deportivo Durango | 0 : 6 | Hayden F. C. | ||
| 13-06-2021 08:00 | C. D. Padua | 2 : 1 | Locos Villahermosa | ||
| 13-06-2021 09:40 | Deportivo River | 3 : 1 | Paris FC | ||
| 13-06-2021 09:40 | Deportivo Niupi | 4 : 2 | Union SC 01 | ||
| 13-06-2021 11:20 | Atlas | 0 : 2 | Cruz Azul | ||
| 13-06-2021 11:20 | Latinos | 3 : 3 | Morelos FC | ||
| 13-06-2021 13:00 | Inter | 2 : 1 | Los Birriondos | ||
| Fecha #8 | 20-06-2021 08:00 | Cerveceros | 1 : 2 | Paris FC | |
| 20-06-2021 08:00 | Deportivo Durango | 0 : 3 | Deportivo Libertadores | ||
| 20-06-2021 08:00 | Hayden F. C. | 4 : 1 | Locos Villahermosa | ||
| 20-06-2021 09:40 | Atlas | 1 : 2 | Deportivo Niupi | ||
| 20-06-2021 09:40 | C. D. Padua | 1 : 0 | Latinos | ||
| 20-06-2021 09:40 | Deportivo River | 1 : 2 | Real Jalisco | ||
| 20-06-2021 11:20 | Cruz Azul | 2 : 2 | Inter | ||
| 20-06-2021 11:20 | Monarcas San Rafael | 1 : 3 | Morelos FC | ||
| 20-06-2021 11:20 | Los Birriondos | 0 : 2 | Union SC 01 | ||
| Fecha #9 | 27-06-2021 08:00 | Locos Villahermosa | 1 : 2 | Union SC 01 | |
| 27-06-2021 08:00 | C. D. Padua | 2 : 2 | Deportivo Libertadores | ||
| 27-06-2021 08:00 | Cerveceros | 0 : 3 | Hayden F. C. | ||
| 27-06-2021 08:00 | Deportivo Durango | 0 : 1 | Deportivo Niupi | ||
| 27-06-2021 09:40 | Latinos | 2 : 1 | Monarcas San Rafael | ||
| 27-06-2021 09:40 | Atlas | 3 : 6 | Deportivo River | ||
| 27-06-2021 09:40 | Cruz Azul | 1 : 3 | Real Jalisco | ||
| 27-06-2021 11:20 | Inter | 0 : 2 | Paris FC | ||
| 27-06-2021 11:20 | Los Birriondos | 0 : 4 | Morelos FC | ||
| Juegos Pendientes | 11-07-2021 00:00 | Han River FC | 1 : 0 | Inter | |
| 11-07-2021 08:00 | C. D. Padua | 5 : 1 | Union SC 01 | ||
| 11-07-2021 09:40 | Deportivo Niupi | 1 : 2 | Real Jalisco | ||
| 11-07-2021 09:40 | Latinos | 4 : 1 | Los Birriondos | ||
| 11-07-2021 11:20 | Cruz Azul | 4 : 3 | Deportivo River | ||
| 11-07-2021 11:20 | Deportivo Libertadores | 1 : 3 | Hayden F. C. | ||
| Fecha #10 | 18-07-2021 08:00 | Paris FC | 0 : 0 | Union SC 01 | |
| 18-07-2021 08:00 | Deportivo Durango | 0 : 5 | Morelos FC | ||
| 18-07-2021 08:00 | Atlas | 1 : 0 | Resto Del Mundo | ||
| 18-07-2021 08:00 | Deportivo Libertadores | 0 : 1 | Locos Villahermosa | ||
| 18-07-2021 09:40 | Cerveceros | 0 : 4 | Cruz Azul | ||
| 18-07-2021 09:40 | C. D. Padua | 4 : 1 | Deportivo Niupi | ||
| 18-07-2021 09:40 | Inter | 3 : 9 | Monarcas San Rafael | ||
| 18-07-2021 09:40 | Real Jalisco | 10 : 0 | Tequileros | ||
| 18-07-2021 11:20 | Deportivo River | 1 : 1 | Morelos FC | ||
| 18-07-2021 11:20 | Hayden F. C. | 4 : 1 | Los Birriondos | ||
| Fecha #11 | 01-08-2021 00:00 | C. D. Padua | 1 : 0 | Morelos FC | |
| 01-08-2021 08:00 | Cerveceros | 2 : 3 | Deportivo Libertadores | ||
| 01-08-2021 08:00 | Locos Villahermosa | 0 : 2 | Resto Del Mundo | ||
| 01-08-2021 08:00 | Deportivo Durango | 2 : 4 | Han River FC | ||
| 01-08-2021 09:40 | Irapuatense | 1 : 3 | Union SC 01 | ||
| 01-08-2021 09:40 | Latinos | 2 : 3 | Real Jalisco | ||
| 01-08-2021 09:40 | Deportivo Niupi | 2 : 4 | Hayden F. C. | ||
| 01-08-2021 11:20 | Atlas | 1 : 0 | Tequileros | ||
| 01-08-2021 11:20 | Deportivo River | 3 : 0 | Inter | ||
| 01-08-2021 11:20 | Los Birriondos | 0 : 4 | Paris FC | ||
| 01-08-2021 13:00 | Cruz Azul | 2 : 6 | Monarcas San Rafael | ||
| Fecha #12 | 08-08-2021 08:00 | Han River FC | 3 : 3 | Locos Villahermosa | |
| 08-08-2021 08:00 | Deportivo Durango | 1 : 1 | Union SC 01 | ||
| 08-08-2021 08:00 | C. D. Padua | 5 : 7 | Resto Del Mundo | ||
| 08-08-2021 09:40 | Irapuatense | 0 : 4 | Morelos FC | ||
| 08-08-2021 09:40 | Deportivo Libertadores | 3 : 2 | Deportivo River | ||
| 08-08-2021 09:40 | Cruz Azul | 2 : 3 | Latinos | ||
| 08-08-2021 11:20 | Atlas | 2 : 4 | Paris FC | ||
| 08-08-2021 11:20 | Cerveceros | 2 : 4 | Los Birriondos | ||
| 08-08-2021 11:20 | Hayden F. C. | 2 : 2 | Real Jalisco | ||
| 08-08-2021 13:00 | Deportivo Niupi | 2 : 4 | Monarcas San Rafael | ||
| Fecha #13 | 22-08-2021 08:00 | Deportivo Libertadores | 4 : 2 | Han River FC | |
| 22-08-2021 08:00 | Locos Villahermosa | 1 : 1 | Monarcas San Rafael | ||
| 22-08-2021 08:00 | Deportivo Durango | 3 : 4 | Resto Del Mundo | ||
| 22-08-2021 09:40 | Morelos FC | 0 : 5 | Real Jalisco | ||
| 22-08-2021 09:40 | C. D. Padua | 1 : 1 | Hayden F. C. | ||
| 22-08-2021 09:40 | Latinos | 3 : 1 | Union SC 01 | ||
| 22-08-2021 09:40 | Cerveceros | 0 : 0 | Irapuatense | ||
| 22-08-2021 11:20 | Cruz Azul | 1 : 1 | Paris FC | ||
| 22-08-2021 11:20 | Atlas | 1 : 3 | Los Birriondos | ||
| 22-08-2021 11:20 | Deportivo Niupi | 1 : 0 | Deportivo River | ||
| Fecha #14 | 29-08-2021 00:00 | Atlas | 1 : 0 | Han River FC | |
| 29-08-2021 08:00 | Cerveceros | 0 : 0 | Latinos | ||
| 29-08-2021 08:00 | Deportivo Libertadores | 6 : 0 | Monarcas San Rafael | ||
| 29-08-2021 08:00 | C. D. Padua | 3 : 1 | Cruz Azul | ||
| 29-08-2021 09:40 | Deportivo River | 4 : 2 | Irapuatense | ||
| 29-08-2021 09:40 | Deportivo Niupi | 3 : 3 | Morelos FC | ||
| 29-08-2021 09:40 | Locos Villahermosa | 0 : 2 | Real Jalisco | ||
| 29-08-2021 11:20 | Hayden F. C. | 5 : 0 | Union SC 01 | ||
| 29-08-2021 11:20 | Paris FC | 2 : 2 | Resto Del Mundo | ||
| 29-08-2021 11:20 | Deportivo Durango | 3 : 2 | Los Birriondos | ||
| Fecha #15 | 05-09-2021 08:00 | Atlas | 6 : 5 | Latinos | |
| 05-09-2021 08:00 | C. D. Padua | 7 : 0 | Los Birriondos | ||
| 05-09-2021 08:00 | Morelos FC | 1 : 2 | Paris FC | ||
| 05-09-2021 09:40 | Deportivo Libertadores | 6 : 0 | Deportivo Niupi | ||
| 05-09-2021 09:40 | Deportivo Durango | 0 : 7 | Real Jalisco | ||
| 05-09-2021 09:40 | Hayden F. C. | 3 : 2 | Resto Del Mundo | ||
| 05-09-2021 09:40 | Han River FC | 3 : 2 | Irapuatense | ||
| 05-09-2021 11:20 | Cruz Azul | 3 : 4 | Locos Villahermosa | ||
| 05-09-2021 11:20 | Monarcas San Rafael | 1 : 5 | Real Jalisco | ||
| 05-09-2021 11:20 | Deportivo River | 2 : 1 | Union SC 01 | ||
| Fecha #16 | 12-09-2021 08:00 | Deportivo Durango | 0 : 0 | Latinos | |
| 12-09-2021 08:00 | Han River FC | 2 : 2 | Paris FC | ||
| 12-09-2021 08:00 | Cruz Azul | 2 : 3 | Deportivo Libertadores | ||
| 12-09-2021 08:00 | Irapuatense | 1 : 1 | Locos Villahermosa | ||
| 12-09-2021 09:40 | Atlas | 3 : 5 | Union SC 01 | ||
| 12-09-2021 09:40 | Cerveceros | 0 : 3 | Morelos FC | ||
| 12-09-2021 09:40 | Deportivo Niupi | 2 : 0 | Los Birriondos | ||
| 12-09-2021 11:20 | Hayden F. C. | 3 : 0 | Monarcas San Rafael | ||
| 12-09-2021 11:20 | C. D. Padua | 2 : 2 | Real Jalisco | ||
| 12-09-2021 11:20 | Deportivo River | 1 : 0 | Resto Del Mundo | ||
| Fecha #17 | 19-09-2021 08:00 | Locos Villahermosa | 4 : 4 | Paris FC | |
| 19-09-2021 08:00 | Deportivo Durango | 3 : 4 | Monarcas San Rafael | ||
| 19-09-2021 08:00 | Deportivo Libertadores | 3 : 1 | Los Birriondos | ||
| 19-09-2021 08:00 | Han River FC | 2 : 3 | Latinos | ||
| 19-09-2021 09:40 | Deportivo Niupi | 1 : 2 | Paris FC | ||
| 19-09-2021 09:40 | Morelos FC | 2 : 2 | Union SC 01 | ||
| 19-09-2021 09:40 | Atlas | 1 : 1 | Deportivo Libertadores | ||
| 19-09-2021 09:40 | Cerveceros | 1 : 7 | Real Jalisco | ||
| 19-09-2021 11:20 | Hayden F. C. | 2 : 2 | Irapuatense | ||
| 19-09-2021 11:20 | Cruz Azul | 1 : 0 | Resto Del Mundo | ||
| 19-09-2021 11:20 | C. D. Padua | 5 : 0 | Deportivo River | ||
| Fecha #18 | 26-09-2021 08:00 | Deportivo Libertadores | 1 : 3 | Latinos | |
| 26-09-2021 08:00 | Monarcas San Rafael | 3 : 0 | Resto Del Mundo | ||
| 26-09-2021 08:00 | Locos Villahermosa | 1 : 2 | Morelos FC | ||
| 26-09-2021 09:40 | Locos Villahermosa | 2 : 1 | Los Birriondos | ||
| 26-09-2021 09:40 | Deportivo Niupi | 4 : 1 | Han River FC | ||
| 26-09-2021 11:20 | Deportivo Durango | 3 : 5 | Irapuatense | ||
| 26-09-2021 11:20 | C. D. Padua | 2 : 1 | Morelos FC | ||
| 26-09-2021 11:20 | Atlas | 2 : 6 | Hayden F. C. | ||
| 26-09-2021 13:00 | Real Jalisco | 10 : 0 | Union SC 01 | ||